Platelets
are key factors in hard and soft tissue repair mechanisms. They provide essential growth factors, such as FGF, PDGF, TGF-ß, EGF, VEGF, IGF, which are involved in stem cell migration, differentiation and proliferation. Additionally, platelets also stimulate fibroblasts and endothelial cells to induce new extracellular matrix deposition and neo-vascularisation respectively.
Plasma
contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors (such as IGF and HGF), and proteins. Among the plasma proteins, the molecules vital for the coagulation process and for the fibrin polymer formation will serve as a scaffold for cell migration. The A-PRP prepared with the Regen BCT device has a very low level of contaminants.
Red blood cells are removed at 99.7 %.
The white blood cell level is drastically reduced, with a preferential depletion (96.7 %) of the pro- inflammatory granulocytes.